Realcomimpute software for multilevel multiple imputation with mixed response types james r. Here i provide a brief history of multiple imputation and relevant software and highlight the contents of the contributions. But while multiple imputation is not available in all the major stats packages, it is very laborintensive to do well. Sep 16, 20 in this paper, we document a study that involved applying a multiple imputation technique with chained equations to data drawn from the 2007 iteration of the timss database. Multiple imputation using chained equations for missing data in. Missing data modeling and bayesian analysis 445 example uses numerical integration in the estimation of the model. Jul 28, 2017 since rubin, multiple imputation has been known to be the standard method of handling missing data graham 2009. Multiple imputation analyses for both descriptive and modelbased analysis. Include software you used to impute, auxiliary variables, etc. Oct 19, 2009 multiple imputation arguably has a steeper learning curve than maximum likelihood, but it too is readily available in familiar software packages. When substituting for a data point, it is known as unit imputation.
Department of biobehavioral health and the prevention research. Reporting the results although the use of multiple imputation and other missing data procedures is increasing, however many modern missing data procedures are still largely misunderstood. Abstract multiple imputation provides a useful strategy for dealing with data sets that have missing values. However, multiple imputation software at the moment has very limited capabilities to impute incomplete count data.
As you add more imputations, your estimates get more precise, meaning they have smaller standard errors ses. The effect of auxiliary variables and multiple imputation on. Jul 20, 2014 higher education researchers using survey data often face decisions about handling missing data. A simple answer is that more imputations are better.
Missing data in surveys and experimental research is a common occurrence which has serious implications on the validity of inferences. The downside for researchers is that some of the recommendations missing data statisticians were making even five years ago have changed. Multiple imputation of bootstrap samples has been implemented in the analyses ofbriggs et al. Single imputation procedures, such as mean imputation, are an improvement but do not account for the uncertainty in the imputations. Analysis that accounts for complex design features, weighting, clustering and stratification.
Several methods of dealing with missing databut also, several less. Multiple imputation for missing data is an attractive method for handling missing data in multivariate analysis. Multiple imputation for missing data statistics solutions. Described in detail by schafer and graham 2002, the missing values are imputed based on the observed values for a given individual and the relations observed in the data for other participants, assuming the observed variables. Multiple imputation of missing covariates with nonlinear effects. Multiple imputation as a flexible tool for missing data handling in. The report ends with a summary of other software available for missing data and a list of the useful references that guided this report.
More precisely, we imputed missing variables contained in the student background datafile for tunisia one of the timss 2007 participating countries, by using van buuren, boshuizen, and knooks sm 18. Our aim in this paper is to apply the multiple imputation technique. Missing data takes many forms and can be attributed to many causes. Mnar is related to the dv, as determined by significant ttests with the dv. Methods specifically targeting missing values in a wide spectrum of statistical analyses are. The effect of auxiliary variables and multiple imputation on parameter estimation in confirmatory factor analysis jin eun yoo educational and psychological measurement 2009 69. Practical missing data analysis issues are discussed, most notably the. As a result, the firsttime user may get lost in a labyrinth of imputation models, missing data mechanisms, multiple versions of the data, pooling, and so on. A comparison of multiple imputation with em algorithm and mcmc method for quality of life missing.
However, the method is still relatively rarely used in epidemiology, perhaps in part because relatively few studies have looked at practical questions about how to implement multiple imputation in large data sets used for diverse purposes. Rather than treating the missing values as known values, multiple imputation. The idea of multiple imputation for missing data was first proposed by rubin 1977. Hope this helps, maarten john graham 2009 missing data analysis. However, the usual advice for multiple imputation for modest fractions of. Multiple imputation using sas software yang yuan sas institute inc. Bayesian simulation methods and hotdeck imputation. Multiple imputation is an effective method for dealing with missing data, and it is becoming increasingly common in many fields. Described in detail by schafer and graham 2002, the missing values are imputed based on the observed values for a given individual and the relations observed in the data for other participants, assuming the observed variables are included in the imputation model. Multiple imputation and maximum likelihood both solve these problems. The diversity of the contributions to this special volume provides an impression about the progress of the last decade in the software development in the multiple imputation.
While the theoretical concept of multiple imputation has been around for decades, the implementation is difficult because making a random draw from the. The second procedure runs the analytic model of interest here it is a linear regression using proc glm within each of the imputed datasets. A case study with the 2008 national ambulatory medical care survey. In this article, we examine the approximation of gelman et al. Lewis t, goldberg e, schenker n, beresovsky v, schappert s, decker s, shimizu i. Instead of lling in a single value for each missing value, a multiple imputation procedure replaces each missing value with a set of plausible values that represent the. This can be computationally demanding depending on the size of the problem. Reporting the use of multiple imputation for missing data in. Multiple imputation using chained equations for missing data.
While complete case analysis may be easy to implement it relies upon stronger missing data assumptions than multiple imputation and it can result in biased estimates and a reduction in power graham, 2009. See enders 2010 for a discussion of other statistical software packages that can perform multiple imputation and other modern missing data procedures. Finally, section 5 explains how to carry out multiple imputation and maximum likelihood using sas and stata. Potential directions for the future of the software development is also provided.
Pdf statistical inference in missing data by mcmc and non. This method ignores the uncertainty existed in the unknown missing values, so it produces biased standard errors of parameter estimates allison, 2001. Multiple imputation mi is considered by many statisticians to be the most appropriate technique for addressing missing data in many circumstances. There are also other software solutions for statistical packages like iveware for sas or ice for stata that support basic count data imputation procedures. The first is proc mi where the user specifies the imputation model to be used and the number of imputed datasets to be created.
Solutions are given for missing data challenges such as handling longitudinal. Realcomimpute software for multilevel multiple imputation. Multiple imputation for continuous and categorical data. A note on bayesian inference after multiple imputation. Multiple imputationnuts and bolts mi can import already imputed data from nhanes or ice, or you can start with original data and form imputations yourself. Advances in statistical procedures provides better and efficient methods of handling missing data yet many researches still handle incomplete data in ways that affects the results negatively. Bootstrap inference when using multiple imputation 3 with multiple imputation for particular analyses. Multiple imputation of incomplete ordinary and overdispersed. After imputations are complete, imputed values within 1 5 can be rounded to 0, and values within.
Either way, dealing with the multiple copies of the data is the bane of mi analysis. Multiple imputation involves filling in the missing values multiple times, creating multiple complete datasets. Other applications of multiple imputation such as disclosure limitation, combining information from multiple data sources, bayesian analysis through prediction, causal. Reporting the use of multiple imputation for missing data. Mediation analysis with missing data through multiple. And maximum likelihood isnt hard or labor intensive, but usually requires using structural equation modeling software, such as amos or mplus. The following is the procedure for conducting the multiple imputation for missing data that was created by rubin in 1987. Schafer and graham 2002 distinguish four general types of single imputation procedures, that is, imputation. Graham 2009 recommends using principal component analysis in order.
Mediation analysis with missing data through multiple imputation and bootstrap lijuan wang, zhiyong zhang, and xin tong university of notre dame introduction mediation models and mediation analysis are widely used in behavioral and social sciences as well as in health and medical research. Model development including interactions with multiple. On the one hand, the interactions are needed to impute the data, while on the other hand, the. Multiple imputation for ordinal variables multiple imputation. Multiple imputation single imputation replaces a missing value with a single imputed value. Graham department of biobehavioral health and the prevention research center, the pennsylvania state university, university park, pennsylvania 16802. In particular, it has been shown to be preferable to listwise deletion, which has historically been a commonly employed method for quantitative. In statistics, imputation is the process of replacing missing data with substituted values. It should be noted that this volume is not intended to be the exclusive source of the multiple imputation software. Mi software that would be developed a decade later. No information is lost, and if the observed data contain information on the missingness, this information can be used to obtain better predictions of the missing values. Multiple imputation to correct for nonresponse bias. The relative impacts of design effects and multiple imputation on variance estimates. Challenges and implications of missing data on the validity.
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